STELARA^® Resources

*The Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system was used to evaluate the level of evidence and strength of recommendations. The level of evidence could range from “high” (very confident that the true effect lies close to the estimate of the effect), “moderate” (moderately confident in the effect estimate; the true effect is likely to be close to the estimate of effect, but there is a possibility that it is substantially different), “low” (confidence in the estimate is limited; the true effect may be substantially different from the estimate of effect), or “very low” (very little confidence in the effect estimate; the true effect is likely to be substantially different from the estimate of effect). “The AGA recommends…” was used for “strong” recommendations (most individuals should receive the recommended course of action; formal decision aids are not likely to be needed to help individuals make decisions consistent with their values and preferences). “The AGA suggests” was used for “conditional” recommendations (different choices would be appropriate for different patients; decision aids may be useful in helping individuals in making decisions consistent with their values and preferences; clinicians should expect to spend more time with patients when working towards a decision).